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Blood Pressure Treatment Slows the Progression of Carotid Stenosis in Patients with Isolated Systolic Hypertension
Stroke 25:44-50, Sutton-Tyrrell,K.,et al, 1994
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Article Abstract
For the primary analysis, 40% of r-proUK patients and 25% of control patients had a modified Rankin score of 2 or less (P = .04). Mortality was 25% for the r-proUK group and 27% for the control group. The recanalization rate was 66% for the r-proUK group and 19% for the control group (P<.001). Intracranial hemorrhage with neurological deterioration within 24 hours occurred in 10% of r-proUK patients and 2% of control patients (P = .06). Despite an increased frequency of early symptoma tic intracranial hemorrhage, treatment with IA r-proUK within 6 hours of the onset of acute ischemic stroke caused by MCA occlusion significantly improved clinical outcome at 90 days.
 
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blood pressure
carotid artery atherosclerosis
carotid artery atherosclerosis,regression
carotid artery disease
carotid artery stenosis
hypertension
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